PDLIM2

2PA1, 3PDV

PDLIM2
PDLIM2
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauPDLIM2, MYSTIQUE, SLIM, PDZ and LIM domain 2
Dynodwyr allanolOMIM: 609722 HomoloGene: 11006 GeneCards: PDLIM2
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

64236

n/a

Ensembl

ENSG00000120913

n/a

UniProt

Q96JY6

n/a

RefSeq (mRNA)

NM_198042
NM_021630
NM_176871
NM_001368120

n/a

RefSeq (protein)

NP_067643
NP_789847
NP_932159
NP_001355049

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PDLIM2 yw PDLIM2 a elwir hefyd yn PDZ and LIM domain protein 2 a PDZ and LIM domain 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 8, band 8p21.3.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PDLIM2.

  • SLIM
  • MYSTIQUE

Llyfryddiaeth

  • "Essential function for PDLIM2 in cell polarization in three-dimensional cultures by feedback regulation of the β1-integrin-RhoA signaling axis. ". Neoplasia. 2014. PMID 24863845.
  • "PDLIM2 regulates transcription factor activity in epithelial-to-mesenchymal transition via the COP9 signalosome. ". Mol Biol Cell. 2014. PMID 24196835.
  • "Global Proteome and Phospho-proteome Analysis of Merlin-deficient Meningioma and Schwannoma Identifies PDLIM2 as a Novel Therapeutic Target. ". EBioMedicine. 2017. PMID 28126595.
  • "Inactivation of the putative ubiquitin-E3 ligase PDLIM2 in classical Hodgkin and anaplastic large cell lymphoma. ". Leukemia. 2017. PMID 27538486.
  • "PDLIM2 suppression efficiently reduces tumor growth and invasiveness of human castration-resistant prostate cancer-like cells.". Prostate. 2016. PMID 26499308.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ PDLIM2 - Cronfa NCBI

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