PDE7A

1ZKL, 3G3N, 4PM0, 4Y2B

PDE7A
PDE7A
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauPDE7A, HCP1, PDE7, phosphodiesterase 7A
Dynodwyr allanolOMIM: 171885 HomoloGene: 1956 GeneCards: PDE7A
EC number3.1.4.53
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

5150

n/a

Ensembl

ENSG00000205268

n/a

UniProt

Q13946

n/a

RefSeq (mRNA)

NM_001242318
NM_002603
NM_002604

n/a

RefSeq (protein)

NP_001229247
NP_002594

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PDE7A yw PDE7A a elwir hefyd yn High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A a Phosphodiesterase 7a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 8, band 8q13.1.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PDE7A.

  • HCP1
  • PDE7

Llyfryddiaeth

  • "Functional characterization of the human phosphodiesterase 7A1 promoter. ". Biochem J. 2003. PMID 12737631.
  • "Ubiquitous expression of phosphodiesterase 7A in human proinflammatory and immune cells. ". Am J Physiol Lung Cell Mol Physiol. 2003. PMID 12388353.
  • "PDE7A1 hydrolyzes cCMP. ". FEBS Lett. 2014. PMID 25128584.
  • "Effects of phosphodiesterase 7 inhibition by RNA interference on the gene expression and differentiation of human mesenchymal stem cell-derived osteoblasts. ". Bone. 2008. PMID 18420479.
  • "Multiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7.". J Biol Chem. 2005. PMID 15994308.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ PDE7A - Cronfa NCBI

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