PCOLCE

PCOLCE
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1UAP
Dynodwyr
Cyfenwau	PCOLCE, PCPE, PCPE-1, PCPE1, procollagen C-endopeptidase enhancer
Dynodwyr allanol	OMIM: 600270 HomoloGene: 1946 GeneCards: PCOLCE
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • heparin binding • GO:0001948, GO:0016582 protein binding • peptidase activator activity • collagen binding • extracellular matrix structural constituent Cydrannau o'r gell • GO:0005578 extracellular matrix • extracellular exosome • extracellular space • extracellular region • collagen-containing extracellular matrix Prosesau biolegol • multicellular organism development • proteolysis • positive regulation of peptidase activity • cellular response to leukemia inhibitory factor Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5118	n/a
Ensembl	ENSG00000106333	n/a
UniProt	Q15113	n/a
RefSeq (mRNA)	NM_002593	n/a
RefSeq (protein)	NP_002584	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PCOLCE yw PCOLCE a elwir hefyd yn Procollagen C-endopeptidase enhancer (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7q22.1.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PCOLCE.

• PCPE
• PCPE1
• PCPE-1

• "Quantification of human serum procollagen C-proteinase enhancer (hsPCPE) glycopattern. ". Clin Chim Acta. 2011. PMID 21569766.
• "Role of the netrin-like domain of procollagen C-proteinase enhancer-1 in the control of metalloproteinase activity. ". J Biol Chem. 2010. PMID 20207734.
• "Nuclear entrapment and extracellular depletion of PCOLCE is associated with muscle degeneration in oculopharyngeal muscular dystrophy. ". BMC Neurol. 2013. PMID 23815790.
• "Procollagen C-proteinase enhancer grasps the stalk of the C-propeptide trimer to boost collagen precursor maturation. ". Proc Natl Acad Sci U S A. 2013. PMID 23550162.
• "Procollagen C-proteinase enhancer stimulates procollagen processing by binding to the C-propeptide region only.". J Biol Chem. 2011. PMID 21940633.