PATZ1

PATZ1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2EPP, 2EPQ, 2EPR, 2EPS, 2YT9
Dynodwyr
Cyfenwau	PATZ1, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG, dJ400N23, POZ/BTB and AT hook containing zinc finger 1
Dynodwyr allanol	OMIM: 605165 HomoloGene: 8636 GeneCards: PATZ1
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding; • DNA binding; • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific; • chromatin binding; • GO:0001948, GO:0016582 protein binding; • metal ion binding; • nucleic acid binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Cydrannau o'r gell	• cnewyllyn cell; • nucleoplasm;
Prosesau biolegol	• regulation of gene expression; • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated; • T cell differentiation; • male gonad development; • GO:0045996 negative regulation of transcription, DNA-templated; • GO:0009373 regulation of transcription, DNA-templated; • transcription by RNA polymerase II; • spermatogenesis; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologau
	23598
	n/a
	ENSG00000100105
	n/a
	Q9HBE1
	n/a
	NM_032052; NM_014323; NM_032050; NM_032051
	n/a
	NP_055138; NP_114439; NP_114440; NP_114441
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PATZ1 yw PATZ1 a elwir hefyd yn POZ/BTB and AT hook containing zinc finger 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q12.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PATZ1.

ZSG
MAZR
PATZ
RIAZ
ZBTB19
ZNF278
dJ400N23

Llyfryddiaeth

"Zinc finger protein 278, a potential oncogene in human colorectal cancer. ". Acta Biochim Biophys Sin (Shanghai). 2008. PMID 18401526.
"PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c. ". Nucleic Acids Res. 2017. PMID 27932482.
"PATZ1 acts as a tumor suppressor in thyroid cancer via targeting p53-dependent genes involved in EMT and cell migration. ". Oncotarget. 2015. PMID 25595894.
"Patz1 regulates embryonic stem cell identity. ". Stem Cells Dev. 2014. PMID 24380431.
"[Association of single nucleotide polymorphisms of PATZ1 gene with azoospermia].". Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2010. PMID 20677143.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] PATZ1 - Cronfa NCBI

[1]

[2]

PATZ1

Cyfystyron

Llyfryddiaeth

Cyfeiriadau

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