PABPC4

PABPC4
Dynodwyr
Cyfenwau	PABPC4, APP-1, APP1, PABP4, iPABP, poly(A) binding protein cytoplasmic 4
Dynodwyr allanol	OMIM: 603407 HomoloGene: 37855 GeneCards: PABPC4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • poly(C) RNA binding • GO:0001948, GO:0016582 protein binding • poly(A) binding • nucleic acid binding • poly(U) RNA binding • RNA binding • mRNA binding • mRNA 3'-UTR binding Cydrannau o'r gell • cytoplasmic stress granule • cnewyllyn cell • cytoplasm • cytosol • ribonucleoprotein complex Prosesau biolegol • GO:0033168, GO:0036404, GO:1902360 RNA processing • RNA catabolic process • blood coagulation • protein biosynthesis • regulation of mRNA stability • myeloid cell development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8761	n/a
Ensembl	ENSG00000090621	n/a
UniProt	Q13310	n/a
RefSeq (mRNA)	NM_003819 NM_001135653 NM_001135654	n/a
RefSeq (protein)	NP_001129125 NP_001129126 NP_003810	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PABPC4 yw PABPC4 a elwir hefyd yn Poly(A) binding protein cytoplasmic 4 a Polyadenylate-binding protein 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p34.3.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PABPC4.

• "Identification and structure of activated-platelet protein-1, a protein with RNA-binding domain motifs that is expressed by activated platelets. ". Eur J Biochem. 1997. PMID 9030741.
• "iPABP, an inducible poly(A)-binding protein detected in activated human T cells. ". Mol Cell Biol. 1995. PMID 8524242.
• "Gender-specific association between the cytoplasmic poly(A) binding protein 4 rs4660293 single nucleotide polymorphism and serum lipid levels. ". Mol Med Rep. 2015. PMID 26005159.
• "Cytoplasmic poly(A) binding protein 4 is highly expressed in human colorectal cancer and correlates with better prognosis. ". J Genet Genomics. 2012. PMID 22884093.
• "Importin alpha-mediated nuclear import of cytoplasmic poly(A) binding protein occurs as a direct consequence of cytoplasmic mRNA depletion.". Mol Cell Biol. 2011. PMID 21646427.