NXT1

NXT1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1JKG, 1JN5, 4WYK
Dynodwyr
Cyfenwau	NXT1, MTR2, P15, nuclear transport factor 2 like export factor 1
Dynodwyr allanol	OMIM: 605811 HomoloGene: 8301 GeneCards: NXT1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cnewyllyn cell • nuclear speck • nuclear pore • nucleoplasm • cytoplasm • cytosol • nuclear pore central transport channel Prosesau biolegol • protein export from nucleus • protein transport • RNA export from nucleus • mRNA export from nucleus • protein import into nucleus • nucleocytoplasmic transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	29107	n/a
Ensembl	ENSG00000132661	n/a
UniProt	Q9UKK6	n/a
RefSeq (mRNA)	NM_013248	n/a
RefSeq (protein)	NP_037380	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NXT1 yw NXT1 a elwir hefyd yn Nuclear transport factor 2 like export factor 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 20, band 20p11.21.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NXT1.

• P15
• MTR2

• "NXT1, a Novel Influenza A NP Binding Protein, Promotes the Nuclear Export of NP via a CRM1-Dependent Pathway. ". Viruses. 2016. PMID 27483302.
• "The principal mRNA nuclear export factor NXF1:NXT1 forms a symmetric binding platform that facilitates export of retroviral CTE-RNA. ". Nucleic Acids Res. 2015. PMID 25628361.
• "Complex formation between Tap and p15 affects binding to FG-repeat nucleoporins and nucleocytoplasmic shuttling. ". J Biol Chem. 2002. PMID 11756420.
• "NXT1 (p15) is a crucial cellular cofactor in TAP-dependent export of intron-containing RNA in mammalian cells. ". Mol Cell Biol. 2001. PMID 11259602.
• "RanGTP-binding protein NXT1 facilitates nuclear export of different classes of RNA in vitro.". Mol Cell Biol. 2000. PMID 10848583.