NUB1

NUB1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WJU
Dynodwyr
Cyfenwau	NUB1, BS4, NUB1L, NYREN18, negative regulator of ubiquitin-like proteins 1, negative regulator of ubiquitin like proteins 1
Dynodwyr allanol	OMIM: 607981 HomoloGene: 41108 GeneCards: NUB1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cnewyllyn cell • cytosol • nucleolus Prosesau biolegol • response to tumor necrosis factor • response to interferon-gamma • positive regulation of proteasomal ubiquitin-dependent protein catabolic process • ubiquitin-dependent protein catabolic process • protein ubiquitination • post-translational protein modification Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	51667	n/a
Ensembl	ENSG00000013374	n/a
UniProt	Q9Y5A7	n/a
RefSeq (mRNA)	NM_001243351 NM_016118 NM_001363529 NM_001385353 NM_001385354 NM_001385355 NM_001385356 NM_001385361	n/a
RefSeq (protein)	NP_001230280 NP_057202 NP_001350458	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NUB1 yw NUB1 a elwir hefyd yn NEDD8 ultimate buster 1 a Negative regulator of ubiquitin like proteins 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7q36.1.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NUB1.

• BS4
• NUB1L
• NYREN18

• "NUB1-mediated targeting of the ubiquitin precursor UbC1 for its C-terminal hydrolysis. ". Eur J Biochem. 2004. PMID 15009209.
• "Regulation of NUB1 Activity through Non-Proteolytic Mdm2-Mediated Ubiquitination. ". PLoS One. 2017. PMID 28099510.
• "Synphilin-1-binding protein NUB1 is colocalized with nonfibrillar, proteinase K-resistant α-synuclein in presynapses in Lewy body disease. ". J Neuropathol Exp Neurol. 2011. PMID 21937912.
• "NUB1, an interferon-inducible protein, mediates anti-proliferative actions and apoptosis in renal cell carcinoma cells through cell-cycle regulation. ". Br J Cancer. 2010. PMID 20160729.
• "Degradation of FAT10 by the 26S proteasome is independent of ubiquitylation but relies on NUB1L.". FEBS Lett. 2009. PMID 19166848.