NAT2

2PFR

NAT2
NAT2
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauNAT2, AAC2, NAT-2, PNAT, N-acetyltransferase 2, N-acetyltransferase 2 (arylamine N-acetyltransferase)
Dynodwyr allanolOMIM: 612182 HomoloGene: 115468 GeneCards: NAT2
EC number2.3.1.5 2.3.1.118, 2.3.1.5
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

10

n/a

Ensembl

ENSG00000156006

n/a

UniProt

P11245

n/a

RefSeq (mRNA)

NM_000015

n/a

RefSeq (protein)

NP_000006

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NAT2 yw NAT2 a elwir hefyd yn N-acetyltransferase 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 8, band 8p22.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NAT2.

  • AAC2
  • PNAT
  • NAT-2

Llyfryddiaeth

  • "Role of N-acetyltransferase 2 acetylation polymorphism in 4, 4'-methylene bis (2-chloroaniline) biotransformation. ". Toxicol Lett. 2018. PMID 29180287.
  • "Genetic polymorphisms of NAT2 and risk of acute myeloid leukemia: A case-control study. ". Medicine (Baltimore). 2017. PMID 29049179.
  • "Association and clinical utility of NAT2 in the prediction of isoniazid-induced liver injury in Singaporean patients. ". PLoS One. 2017. PMID 29036176.
  • "Association between NAT2 polymorphisms and the risk of schizophrenia in a Northern Chinese Han population. ". Psychiatr Genet. 2017. PMID 28187106.
  • "Association between N-Acetyltransferase 2 Polymorphism and Bladder Cancer Risk: a Meta-Analysis in a Single Ethnic Group.". Clin Lab. 2017. PMID 28182356.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ NAT2 - Cronfa NCBI

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