MXD1

MXD1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1E91, 1G1E, 1NLW, 1PD7, 1S5Q
Dynodwyr
Cyfenwau	MXD1, BHLHC58, MAD, MAD1, MAX dimerization protein 1
Dynodwyr allanol	OMIM: 600021 HomoloGene: 1767 GeneCards: MXD1
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding; • DNA binding; • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific; • GO:0001948, GO:0016582 protein binding; • GO:0001104 transcription coregulator activity; • protein dimerization activity; • GO:0001106 transcription corepressor activity; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Cydrannau o'r gell	• cnewyllyn cell; • nucleoplasm; • mitocondria; • cytosol;
Prosesau biolegol	• multicellular organism development; • cell population proliferation; • GO:0009373 regulation of transcription, DNA-templated; • GO:1901227 negative regulation of transcription by RNA polymerase II; • transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologau
	4084
	n/a
	ENSG00000059728
	n/a
	Q05195
	n/a
	NM_002357; NM_001202513; NM_001202514
	n/a
	NP_001189442; NP_001189443; NP_002348
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MXD1 yw MXD1 a elwir hefyd yn MAX dimerization protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2p13.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MXD1.

MAD
MAD1
BHLHC58

Llyfryddiaeth

"Effect of the transcriptional repressor Mad1 on proliferation of human melanoma cells. ". Exp Dermatol. 2002. PMID 12366697.
"Assignment of the human MAD and MXI1 genes to chromosomes 2p12-p13 and 10q24-q25. ". Genomics. 1994. PMID 7829091.
"miR-382-5p Controls Hematopoietic Stem Cell Differentiation Through the Downregulation of MXD1. ". Stem Cells Dev. 2016. PMID 27520398.
"TCP10L synergizes with MAD1 in transcriptional suppression and cell cycle arrest through mutual interaction. ". BMB Rep. 2016. PMID 26698869.
"The suppression of MAD1 by AKT-mediated phosphorylation activates MAD1 target genes transcription.". Mol Carcinog. 2009. PMID 19526459.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] MXD1 - Cronfa NCBI

[1]

[2]

MXD1

Cyfystyron

Llyfryddiaeth

Cyfeiriadau

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