MRPL12

MRPL12
Dynodwyr
Cyfenwau	MRPL12, 5c5-2, L12mt, MRP-L31/34, MRPL7, MRPL7/L12, RPML12, mitochondrial ribosomal protein L12
Dynodwyr allanol	OMIM: 602375 HomoloGene: 2212 GeneCards: MRPL12
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • structural constituent of ribosome • GO:0001948, GO:0016582 protein binding • RNA binding Cydrannau o'r gell • mitochondrial inner membrane • ribosom • intracellular anatomical structure • mitochondrial large ribosomal subunit • mitocondria Prosesau biolegol • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • mitochondrial transcription • mitochondrial translational elongation • mitochondrial translational termination • protein biosynthesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6182	n/a
Ensembl	ENSG00000262814	n/a
UniProt	P52815	n/a
RefSeq (mRNA)	NM_002949	n/a
RefSeq (protein)	NP_002940	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MRPL12 yw MRPL12 a elwir hefyd yn Mitochondrial ribosomal protein L12 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q25.3.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MRPL12.

• "Mitochondrial Ribosomal Protein L12 Is Required for POLRMT Stability and Exists as Two Forms Generated by Alternative Proteolysis during Import. ". J Biol Chem. 2016. PMID 26586915.
• "Human mitochondrial ribosomal protein MRPL12 interacts directly with mitochondrial RNA polymerase to modulate mitochondrial gene expression. ". J Biol Chem. 2007. PMID 17337445.
• "Mutations in mitochondrial ribosomal protein MRPL12 leads to growth retardation, neurological deterioration and mitochondrial translation deficiency. ". Biochim Biophys Acta. 2013. PMID 23603806.
• "Expression and human chromosomal localization to 17q25 of the growth-regulated gene encoding the mitochondrial ribosomal protein MRPL12. ". Genomics. 1997. PMID 9169145.
• "A delayed-early response nuclear gene encoding MRPL12, the mitochondrial homologue to the bacterial translational regulator L7/L12 protein.". J Biol Chem. 1996. PMID 8626705.