MPZ

MPZ
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3OAI
Dynodwyr
Cyfenwau	MPZ, CHM, CMT1, CMT1B, CMT2I, CMT2J, CMT4E, CMTDI3, CMTDID, DSS, HMSNIB, MPP, P0, myelin protein zero, CHN2
Dynodwyr allanol	OMIM: 159440 HomoloGene: 445 GeneCards: MPZ
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • structural molecule activity Cydrannau o'r gell • integral component of membrane • myelin sheath • rough endoplasmic reticulum • lysosome • basolateral plasma membrane • integral component of plasma membrane • bilen • cellbilen Prosesau biolegol • negative regulation of apoptotic process • chemical synaptic transmission • myelination • cell-cell adhesion via plasma-membrane adhesion molecules • cell aggregation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4359	n/a
Ensembl	ENSG00000158887	n/a
UniProt	P25189	n/a
RefSeq (mRNA)	NM_000530 NM_001315491	n/a
RefSeq (protein)	NP_000521 NP_001302420	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MPZ yw MPZ a elwir hefyd yn Myelin protein zero (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q23.3.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MPZ.

• "Genotype-phenotype characteristics and baseline natural history of heritable neuropathies caused by mutations in the MPZ gene. ". Brain. 2015. PMID 26310628.
• "Impact of I30T and I30M substitution in MPZ gene associated with Dejerine-Sottas syndrome type B (DSSB): A molecular modeling and dynamics. ". J Theor Biol. 2015. PMID 26135405.
• "A Costa Rican family affected with Charcot-Marie-Tooth disease due to the myelin protein zero (MPZ) p.Thr124Met mutation shares the Belgian haplotype. ". Rev Biol Trop. 2014. PMID 25720167.
• "Myelin protein zero and its antibody in serum as biomarkers of n-hexane-induced peripheral neuropathy and neurotoxicity effects. ". Chin Med J (Engl). 2014. PMID 24762602.
• "Two novel MPZ mutations in Chinese CMT patients.". J Peripher Nerv Syst. 2013. PMID 24028194.