MMP10

MMP10
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1Q3A, 3V96, 4ILW
Dynodwyr
Cyfenwau	MMP10, SL-2, STMY2, matrix metallopeptidase 10
Dynodwyr allanol	OMIM: 185260 HomoloGene: 20546 GeneCards: MMP10
EC number	3.4.24.22
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • zinc ion binding • GO:0070122 peptidase activity • metalloendopeptidase activity • hydrolase activity • metallopeptidase activity • metal ion binding • serine-type endopeptidase activity Cydrannau o'r gell • extracellular region • extracellular space • GO:0005578 extracellular matrix Prosesau biolegol • collagen catabolic process • extracellular matrix disassembly • regulation of cell migration • proteolysis • response to hypoxia • extracellular matrix organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4319	n/a
Ensembl	ENSG00000166670	n/a
UniProt	P09238	n/a
RefSeq (mRNA)	NM_002425	n/a
RefSeq (protein)	NP_002416	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MMP10 yw MMP10 a elwir hefyd yn Stromelysin-2 a Matrix metallopeptidase 10 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q22.2.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MMP10.

• SL-2
• STMY2

• "Role of Stromelysin 2 (Matrix Metalloproteinase 10) as a Novel Mediator of Vascular Remodeling Underlying Pulmonary Hypertension Associated With Systemic Sclerosis. ". Arthritis Rheumatol. 2017. PMID 28805015.
• "Differential immunohistochemical expression of matrix metalloproteinase-10 (MMP-10) in non-melanoma skin cancers of the head and neck. ". Pathol Res Pract. 2016. PMID 27567711.
• "Matrix metalloproteinase-10 regulates stemness of ovarian cancer stem-like cells by activation of canonical Wnt signaling and can be a target of chemotherapy-resistant ovarian cancer. ". Oncotarget. 2016. PMID 27072580.
• "Protein Expression of Stromelysin-2 in Head and Neck Squamous Cell Carcinomas. ". Asian Pac J Cancer Prev. 2015. PMID 26625808.
• "Association of matrix metalloproteinase-10 polymorphisms with susceptibility to pelvic organ prolapse.". J Obstet Gynaecol Res. 2015. PMID 26419737.