LASP1

LASP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3I35
Dynodwyr
Cyfenwau	LASP1, MLN50, LIM and SH3 protein 1, LASP-1
Dynodwyr allanol	OMIM: 602920 HomoloGene: 4480 GeneCards: LASP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • ion transmembrane transporter activity • actin filament binding • actin binding • GO:0001948, GO:0016582 protein binding • metal ion binding • cadherin binding Cydrannau o'r gell • cell cortex • extracellular exosome • Cytosgerbwd • focal adhesion • cortical actin cytoskeleton • cytoplasm Prosesau biolegol • cludo transmembrane rhwng ïonau • cludo ïon • positive regulation of signal transduction • GO:0015915 transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3927	n/a
Ensembl	ENSG00000002834	n/a
UniProt	Q14847	n/a
RefSeq (mRNA)	NM_001271608 NM_006148	n/a
RefSeq (protein)	NP_001258537 NP_006139	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LASP1 yw LASP1 a elwir hefyd yn LIM and SH3 protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q12.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn LASP1.

• MLN50
• Lasp-1

• "Paving the path for invasion: The polyedric role of LASP1 in cancer. ". Tumour Biol. 2017. PMID 28621232.
• "Upregulated LASP-1 correlates with a malignant phenotype and its potential therapeutic role in human cholangiocarcinoma. ". Tumour Biol. 2016. PMID 26729195.
• "The cytoskeletal protein LASP-1 differentially regulates migratory activities of choriocarcinoma cells. ". Arch Gynecol Obstet. 2016. PMID 26232936.
• "LASP1, a Newly Identified Melanocytic Protein with a Possible Role in Melanin Release, but Not in Melanoma Progression. ". PLoS One. 2015. PMID 26061439.
• "Molecular characterization of LASP-1 expression reveals vimentin as its new partner in human hepatocellular carcinoma cells.". Int J Oncol. 2015. PMID 25760690.