IL5RA

IL5RA
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1OBX, 1OBZ, 3QT2, 3VA2
Dynodwyr
Cyfenwau	IL5RA, CD125, CDw125, HSIL5R3, IL5R, Interleukin 5 receptor alpha subunit, interleukin 5 receptor subunit alpha
Dynodwyr allanol	OMIM: 147851 HomoloGene: 473 GeneCards: IL5RA
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • interleukin-5 receptor activity • GO:0001948, GO:0016582 protein binding • GO:0016518 cytokine receptor activity • protein tyrosine kinase activity • GO:0019974 cytokine binding Cydrannau o'r gell • integral component of membrane • bilen • cellbilen • intracellular anatomical structure • extracellular space • external side of plasma membrane • receptor complex Prosesau biolegol • cellular response to organic substance • inflammatory response to antigenic stimulus • regulation of interleukin-5 production • MAPK cascade • cell population proliferation • GO:0072468 signal transduction • interleukin-5-mediated signaling pathway • peptidyl-tyrosine phosphorylation • cytokine-mediated signaling pathway • positive regulation of leukocyte proliferation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3568	n/a
Ensembl	ENSG00000091181	n/a
UniProt	Q01344	n/a
RefSeq (mRNA)	NM_000564 NM_001243099 NM_175724 NM_175725 NM_175726 NM_175727 NM_175728	n/a
RefSeq (protein)	NP_000555 NP_001230028 NP_783851 NP_783852 NP_783853 NP_783854 NP_783855	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IL5RA yw IL5RA a elwir hefyd yn Interleukin-5 receptor subunit alpha (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3p26.2.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IL5RA.

• "IL5RA polymorphisms, smoking and eczema in Japanese women: the Kyushu Okinawa Maternal and Child Health Study. ". Int J Immunogenet. 2015. PMID 25523412.
• "Case-control study of rhinoconjunctivitis associated with IL5RA polymorphisms in Japanese women: the Kyushu Okinawa Maternal and Child Health Study. ". Cytokine. 2014. PMID 24332579.
• "A genetic effect of IL-5 receptor α polymorphism in patients with aspirin-exacerbated respiratory disease. ". Exp Mol Med. 2013. PMID 23470716.
• "Increased serum-soluble interleukin-5 receptor alpha level precedes the development of eczema in children. ". Pediatr Allergy Immunol. 2010. PMID 20735756.
• "Differential expression of the interleukin 5 receptor alpha isoforms in blood and tissue eosinophils of nasal polyp patients.". Allergy. 2009. PMID 19170670.