HSPG2

HSPG2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3SH4, 3SH5
Dynodwyr
Cyfenwau	HSPG2, HSPG, PLC, PRCAN, SJA, SJS, SJS1, heparan sulfate proteoglycan 2
Dynodwyr allanol	OMIM: 142461 HomoloGene: 68473 GeneCards: HSPG2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • metal ion binding • GO:0001948, GO:0016582 protein binding • calcium ion binding • protein C-terminus binding • amyloid-beta binding • extracellular matrix structural constituent conferring compression resistance • low-density lipoprotein particle receptor binding Cydrannau o'r gell • basement membrane • Golgi lumen • extracellular exosome • lysosomal lumen • extracellular region • cellbilen • GO:0005578 extracellular matrix • focal adhesion • extracellular space • collagen-containing extracellular matrix • plasma membrane protein complex Prosesau biolegol • glycosaminoglycan metabolic process • extracellular matrix disassembly • retinoid metabolic process • glycosaminoglycan biosynthetic process • glycosaminoglycan catabolic process • angiogenesis • extracellular matrix organization • lipid metabolism • receptor-mediated endocytosis • inflammatory response • brain development • negative regulation of angiogenesis • cell differentiation • animal organ morphogenesis • tissue development • cell migration • substrate adhesion-dependent cell spreading Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3339	n/a
Ensembl	ENSG00000142798	n/a
UniProt	P98160	n/a
RefSeq (mRNA)	NM_001291860 NM_005529	n/a
RefSeq (protein)	NP_001278789 NP_005520	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HSPG2 yw HSPG2 a elwir hefyd yn Heparan sulfate proteoglycan 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p36.12.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HSPG2.

• "Can rs3767140 SNP of the perlecan (HSPG2) gene affect the diabetes mellitus through the dyslipidemia?". Cell Mol Biol (Noisy-le-grand). 2016. PMID 27545212.
• "Endorepellin-evoked Autophagy Contributes to Angiostasis. ". J Biol Chem. 2016. PMID 27435676.
• "The CS Sulfation Motifs 4C3, 7D4, 3B3[-]; and Perlecan Identify Stem Cell Populations and Their Niches, Activated Progenitor Cells and Transitional Areas of Tissue Development in the Fetal Human Elbow. ". Stem Cells Dev. 2016. PMID 27068010.
• "Perlecan expression influences the keratin 15-positive cell population fate in the epidermis of aging skin. ". Aging (Albany NY). 2016. PMID 26996820.
• "What maintains the high intra-follicular estradiol concentration in pre-ovulatory follicles?". J Assist Reprod Genet. 2016. PMID 26552664.