HOXA7

HOXA7
Dynodwyr
Cyfenwau	HOXA7, ANTP, HOX1, HOX1.1, HOX1A, homeobox A7
Dynodwyr allanol	OMIM: 142950 HomoloGene: 56001 GeneCards: HOXA7
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• sequence-specific DNA binding; • DNA binding; • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific; • transcription factor binding; • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific; • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;
Cydrannau o'r gell	• cnewyllyn cell; • nucleoplasm; • nuclear membrane;
Prosesau biolegol	• embryonic skeletal system morphogenesis; • negative regulation of monocyte differentiation; • negative regulation of keratinocyte differentiation; • GO:0009373 regulation of transcription, DNA-templated; • GO:1901227 negative regulation of transcription by RNA polymerase II; • stem cell differentiation; • transcription, DNA-templated; • negative regulation of cell-matrix adhesion; • multicellular organism development; • angiogenesis; • GO:0045996 negative regulation of transcription, DNA-templated; • negative regulation of leukocyte migration; • anterior/posterior pattern specification; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologau
	3204
	n/a
	ENSG00000122592
	n/a
	P31268
	n/a
	NM_006896
	n/a
	NP_008827
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HOXA7 yw HOXA7 a elwir hefyd yn Homeobox A7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7p15.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HOXA7.

ANTP
HOX1
HOX1A
HOX1.1

Llyfryddiaeth

"HOXA7 plays a critical role in metastasis of liver cancer associated with activation of Snail. ". Mol Cancer. 2016. PMID 27600149.
"All-trans retinoic acid inhibits HOXA7 expression in leukemia cell NB4. ". Cell Mol Biol (Noisy-le-grand). 2016. PMID 26828989.
"Pentapeptide insertion mutagenesis of the Hoxa1 protein: mapping of transcription activation and DNA-binding regulatory domains. ". J Cell Biochem. 2010. PMID 20336696.
"HOXA7 in epithelial ovarian cancer: interrelationships between differentiation and clinical features. ". Reprod Sci. 2007. PMID 17959889.
"Sequence analysis and tissue specific expression of human HOXA7.". Mol Biotechnol. 2000. PMID 10911612.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] HOXA7 - Cronfa NCBI

[1]

[2]

HOXA7

Cyfystyron

Llyfryddiaeth

Cyfeiriadau

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