GZMM

2ZGC, 2ZGH, 2ZGJ, 2ZKS

GZMM
GZMM
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauGZMM, LMET1, MET1, granzyme M
Dynodwyr allanolOMIM: 600311 HomoloGene: 21099 GeneCards: GZMM
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

3004

n/a

Ensembl

ENSG00000197540

n/a

UniProt

P51124

n/a

RefSeq (mRNA)

NM_005317
NM_001258351

n/a

RefSeq (protein)

NP_001245280
NP_005308

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GZMM yw GZMM a elwir hefyd yn Granzyme M (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19p13.3.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GZMM.

  • MET1
  • LMET1

Llyfryddiaeth

  • "Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling. ". Biochem Biophys Res Commun. 2016. PMID 27133719.
  • "Elevated granzyme M-expressing lymphocytes during cytomegalovirus latency and reactivation after allogeneic stem cell transplantation. ". Clin Immunol. 2014. PMID 24316590.
  • "Noncytotoxic inhibition of cytomegalovirus replication through NK cell protease granzyme M-mediated cleavage of viral phosphoprotein 71. ". J Immunol. 2010. PMID 21059895.
  • "Granzyme M: characterization with sites of post-translational modification and specific sites of interaction with substrates and inhibitors. ". Mol Biol Rep. 2011. PMID 20107908.
  • "The cytotoxic protease granzyme M is expressed by lymphocytes of both the innate and adaptive immune system.". Mol Immunol. 2010. PMID 19896187.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ GZMM - Cronfa NCBI

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