GSTA3

1TDI, 2VCV

GSTA3
GSTA3
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauGSTA3, GSTA3-3, GTA3, glutathione S-transferase alpha 3
Dynodwyr allanolOMIM: 605449 HomoloGene: 37355 GeneCards: GSTA3
EC number2.5.1.18
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

2940

n/a

Ensembl

ENSG00000174156

n/a

UniProt

Q16772

n/a

RefSeq (mRNA)

NM_000847
NM_001363542

n/a

RefSeq (protein)

NP_000838
NP_001350471

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GSTA3 yw GSTA3 a elwir hefyd yn Glutathione S-transferase alpha 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p12.2.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GSTA3.

  • GTA3
  • GSTA3-3

Llyfryddiaeth

  • "The isomerization of Δ5-androstene-3,17-dione by the human glutathione transferase A3-3 proceeds via a conjugated heteroannular diene intermediate. ". J Biol Chem. 2014. PMID 25248748.
  • "Isomerization of Δ5-androstene-3,17-dione into Δ4-androstene-3,17-dione catalyzed by human glutathione transferase A3-3: a computational study identifies a dual role for glutathione. ". J Phys Chem A. 2014. PMID 24739064.
  • "Targeting human glutathione transferase A3-3 attenuates progesterone production in human steroidogenic cells. ". Biochem J. 2008. PMID 18426392.
  • "Mutation analyses of genes on 6p12-p11 in patients with juvenile myoclonic epilepsy. ". Neurosci Lett. 2006. PMID 16876319.
  • "Crystal structure of human glutathione S-transferase A3-3 and mechanistic implications for its high steroid isomerase activity.". Biochemistry. 2004. PMID 15595823.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ GSTA3 - Cronfa NCBI

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