GRB14

2AUG, 2AUH, 4K81

GRB14
GRB14
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauGRB14, growth factor receptor bound protein 14
Dynodwyr allanolOMIM: 601524 HomoloGene: 3303 GeneCards: GRB14
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

2888

n/a

Ensembl

ENSG00000115290

n/a

UniProt

Q14449

n/a

RefSeq (mRNA)

NM_001303422
NM_004490

n/a

RefSeq (protein)

NP_001290351
NP_004481

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GRB14 yw GRB14 a elwir hefyd yn Growth factor receptor bound protein 14 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2q24.3.[2]

Llyfryddiaeth

  • "Phosphorylation of clustered serine residues in the N-terminus of BPS domain negatively regulates formation of the complex between human Grb14 and insulin receptor. ". J Biochem. 2017. PMID 28130417.
  • "High expression of growth factor receptor-bound protein 14 predicts poor prognosis for colorectal cancer patients. ". Biotechnol Lett. 2016. PMID 26965150.
  • "Identifying candidate genes for Type 2 Diabetes Mellitus and obesity through gene expression profiling in multiple tissues or cells. ". J Diabetes Res. 2013. PMID 24455749.
  • "Pleiotropic effects of obesity-susceptibility loci on metabolic traits: a meta-analysis of up to 37,874 individuals. ". Diabetologia. 2013. PMID 23827965.
  • "The insulin resistance Grb14 adaptor protein promotes thyroid cancer ret signaling and progression.". Oncogene. 2012. PMID 22158039.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ GRB14 - Cronfa NCBI

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