GPX7

2P31

GPX7
GPX7
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauGPX7, CL683, GPX6, GPx-7, GSHPx-7, NPGPx, glutathione peroxidase 7
Dynodwyr allanolOMIM: 615784 HomoloGene: 128491 GeneCards: GPX7
EC number5.3.4.1
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

2882

n/a

Ensembl

ENSG00000116157

n/a

UniProt

Q96SL4

n/a

RefSeq (mRNA)

NM_015696

n/a

RefSeq (protein)

NP_056511

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GPX7 yw GPX7 a elwir hefyd yn Glutathione peroxidase 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p32.3.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GPX7.

  • GPX6
  • CL683
  • GPx-7
  • NPGPx
  • GSHPx-7

Llyfryddiaeth

  • "Loss of glutathione peroxidase 7 promotes TNF-α-induced NF-κB activation in Barrett's carcinogenesis. ". Carcinogenesis. 2014. PMID 24692067.
  • "Glutathione peroxidase 7 has potential tumour suppressor functions that are silenced by location-specific methylation in oesophageal adenocarcinoma. ". Gut. 2014. PMID 23580780.
  • "Identification of a novel putative non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) essential for alleviating oxidative stress generated from polyunsaturated fatty acids in breast cancer cells. ". J Biol Chem. 2004. PMID 15294905.
  • "GPX4 and GPX7 over-expression in human hepatocellular carcinoma tissues. ". Eur J Histochem. 2015. PMID 26708178.
  • "Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human.". EMBO Mol Med. 2013. PMID 23828861.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ GPX7 - Cronfa NCBI

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