GPX2

2HE3

GPX2
GPX2
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauGPX2, GI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPX-GI, GSHPx-2, glutathione peroxidase 2
Dynodwyr allanolOMIM: 138319 HomoloGene: 20479 GeneCards: GPX2
EC number1.11.1.9 1.11.1.12, 1.11.1.9
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

2877

n/a

Ensembl

ENSG00000176153

n/a

UniProt

P18283

n/a

RefSeq (mRNA)

NM_002083

n/a

RefSeq (protein)

NP_002074

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GPX2 yw GPX2 a elwir hefyd yn Glutathione peroxidase 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 14, band 14q23.3.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GPX2.

  • GPRP
  • GPx-2
  • GI-GPx
  • GPRP-2
  • GPx-GI
  • GSHPx-2
  • GSHPX-GI

Llyfryddiaeth

  • "GPX2 overexpression indicates poor prognosis in patients with hepatocellular carcinoma. ". Tumour Biol. 2017. PMID 28635398.
  • "Prognostic significance of glutathione peroxidase 2 in gastric carcinoma. ". Tumour Biol. 2017. PMID 28631563.
  • "Clinicopathological and prognostic significance of GPX2 protein expression in esophageal squamous cell carcinoma. ". BMC Cancer. 2016. PMID 27388201.
  • "GPX2 underexpression indicates poor prognosis in patients with urothelial carcinomas of the upper urinary tract and urinary bladder. ". World J Urol. 2015. PMID 25813210.
  • "GPx2 suppression of H2O2 stress links the formation of differentiated tumor mass to metastatic capacity in colorectal cancer.". Cancer Res. 2014. PMID 25261240.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ GPX2 - Cronfa NCBI

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