FGF7

FGF7
Dynodwyr
Cyfenwau	FGF7, HBGF-7, KGF, fibroblast growth factor 7
Dynodwyr allanol	OMIM: 148180 HomoloGene: 7316 GeneCards: FGF7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • heparin binding • fibroblast growth factor receptor binding • GO:0001948, GO:0016582 protein binding • chemoattractant activity • growth factor activity • 1-phosphatidylinositol-3-kinase activity • protein tyrosine kinase activity • phosphatidylinositol-4,5-bisphosphate 3-kinase activity Cydrannau o'r gell • Golgi apparatus • extracellular region Prosesau biolegol • actin cytoskeleton reorganization • mesenchymal cell proliferation • positive regulation of keratinocyte proliferation • positive regulation of epithelial cell proliferation involved in lung morphogenesis • secretion by lung epithelial cell involved in lung growth • positive regulation of epithelial cell proliferation • regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling • MAPK cascade • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • fibroblast growth factor receptor signaling pathway • positive regulation of keratinocyte migration • protein localization to cell surface • response to wounding • positive regulation of cell population proliferation • epidermis development • positive regulation of peptidyl-tyrosine phosphorylation • hair follicle morphogenesis • positive chemotaxis • positive regulation of cell division • GO:0072468 signal transduction • branching involved in salivary gland morphogenesis • phosphatidylinositol phosphate biosynthetic process • peptidyl-tyrosine phosphorylation • phosphatidylinositol-3-phosphate biosynthetic process • regulation of signaling receptor activity • positive regulation of protein kinase B signaling Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2252	n/a
Ensembl	ENSG00000140285	n/a
UniProt	P21781	n/a
RefSeq (mRNA)	NM_002009	n/a
RefSeq (protein)	NP_002000	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FGF7 yw FGF7 a elwir hefyd yn Fibroblast growth factor 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 15, band 15q21.2.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FGF7.

• KGF
• HBGF-7

• "In silico enhancement of the stability and activity of keratinocyte growth factor. ". J Theor Biol. 2017. PMID 28093295.
• "Role of Keratinocyte Growth Factor in the Differentiation of Sweat Gland-Like Cells From Human Umbilical Cord-Derived Mesenchymal Stem Cells. ". Stem Cells Transl Med. 2016. PMID 26574554.
• "FGF7 Over Expression is an Independent Prognosticator in Patients with Urothelial Carcinoma of the Upper Urinary Tract and Bladder. ". J Urol. 2015. PMID 25623741.
• "In vivo over-expression of KGF mimic human middle ear cholesteatoma. ". Eur Arch Otorhinolaryngol. 2015. PMID 25138153.
• "Recombinant keratinocyte growth factor 1 in tobacco potentially promotes wound healing in diabetic rats.". Biomed Res Int. 2014. PMID 24783215.