DAPP1

DAPP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1FAO, 1FB8
Dynodwyr
Cyfenwau	DAPP1, BAM32, dual adaptor of phosphotyrosine and 3-phosphoinositides, dual adaptor of phosphotyrosine and 3-phosphoinositides 1
Dynodwyr allanol	OMIM: 605768 HomoloGene: 32138 GeneCards: DAPP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • phospholipid binding • phosphatidylinositol-3,4,5-trisphosphate binding • phosphatidylinositol-3,4-bisphosphate binding • PDZ domain binding Cydrannau o'r gell • cytosol • cellbilen • bilen • cytoplasm Prosesau biolegol • GO:0016576 protein dephosphorylation • GO:0072468 signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	27071	n/a
Ensembl	ENSG00000070190	n/a
UniProt	Q9UN19	n/a
RefSeq (mRNA)	NM_001306151 NM_014395	n/a
RefSeq (protein)	NP_001293080 NP_055210	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DAPP1 yw DAPP1 a elwir hefyd yn Dual adaptor of phosphotyrosine and 3-phosphoinositides 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 4, band 4q23.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DAPP1.

• BAM32

• "Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains. ". Mol Cell. 2000. PMID 10983984.
• "The adaptor protein Bam32 regulates Rac1 activation and actin remodeling through a phosphorylation-dependent mechanism. ". J Biol Chem. 2004. PMID 15247305.
• "The adaptor protein Bam32 in human dendritic cells participates in the regulation of MHC class I-induced CD8+ T cell activation. ". J Immunol. 2011. PMID 21930970.
• "The B lymphocyte adaptor molecule of 32 kilodaltons (Bam32) regulates B cell antigen receptor internalization. ". J Immunol. 2004. PMID 15494510.
• "The B lymphocyte adaptor molecule of 32 kD (Bam32) regulates B cell antigen receptor signaling and cell survival.". J Exp Med. 2002. PMID 11781373.