CRP

CRP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1B09, 1GNH, 1LJ7, 3L2Y, 3PVN, 3PVO
Dynodwyr
Cyfenwau	CRP, PTX1, C-reactive protein, pentraxin-related, C-Reactive Protein
Dynodwyr allanol	OMIM: 123260 HomoloGene: 128039 GeneCards: CRP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • low-density lipoprotein particle receptor binding • calcium ion binding • virion binding • complement component C1q complex binding • GO:0001948, GO:0016582 protein binding • metal ion binding • low-density lipoprotein particle binding • choline binding • identical protein binding Cydrannau o'r gell • extracellular region • extracellular space Prosesau biolegol • negative regulation of lipid storage • positive regulation of superoxide anion generation • GO:1901313 positive regulation of gene expression • inflammatory response • acute-phase response • negative regulation of macrophage derived foam cell differentiation • opsonization • GO:0051637 defense response to Gram-positive bacterium • complement activation, classical pathway • innate immune response Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1401	n/a
Ensembl	ENSG00000132693	n/a
UniProt	P02741	n/a
RefSeq (mRNA)	NM_000567 NM_001329057 NM_001329058 NM_001382703	n/a
RefSeq (protein)	NP_000558 NP_001315986 NP_001315987 NP_001369632	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CRP yw CRP a elwir hefyd yn C-reactive protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q23.2.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CRP.

• PTX1

• "C-Reactive Protein (CRP) is a Promising Diagnostic Immunohistochemical Marker for Intrahepatic Cholangiocarcinoma and is Associated With Better Prognosis. ". Am J Surg Pathol. 2017. PMID 28945626.
• "Maternal serum C-reactive protein concentration and intra-amniotic inflammation in women with preterm prelabor rupture of membranes. ". PLoS One. 2017. PMID 28813455.
• "Association of C-Reactive Protein Genetic Polymorphisms With Late Age-Related Macular Degeneration. ". JAMA Ophthalmol. 2017. PMID 28750115.
• "The long-term relationship between dietary pantothenic acid (vitamin B5) intake and C-reactive protein concentration in adults aged 40 years and older. ". Nutr Metab Cardiovasc Dis. 2017. PMID 28739188.
• "Coronary artery disease-associated genetic variants and biomarkers of inflammation.". PLoS One. 2017. PMID 28686695.