CPA4

2BO9, 2BOA, 2PCU, 4A94, 4BD9

CPA4
CPA4
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauCPA4, CPA3, carboxypeptidase A4
Dynodwyr allanolOMIM: 607635 HomoloGene: 56753 GeneCards: CPA4
Patrwm RNA pattern


Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

51200

n/a

Ensembl

n/a

n/a

UniProt

Q9UI42

n/a

RefSeq (mRNA)

NM_016352
NM_001163446

n/a

RefSeq (protein)

NP_001156918
NP_057436

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CPA4 yw CPA4 a elwir hefyd yn Carboxypeptidase A4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7q32.2.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CPA4.

  • CPA3

Llyfryddiaeth

  • "Detailed molecular comparison between the inhibition mode of A/B-type carboxypeptidases in the zymogen state and by the endogenous inhibitor latexin. ". Cell Mol Life Sci. 2005. PMID 16091843.
  • "Characterization of the substrate specificity of human carboxypeptidase A4 and implications for a role in extracellular peptide processing. ". J Biol Chem. 2010. PMID 20385563.
  • "A noncanonical mechanism of carboxypeptidase inhibition revealed by the crystal structure of the Tri-Kunitz SmCI in complex with human CPA4. ". Structure. 2013. PMID 23746805.
  • "Crystal structure of novel metallocarboxypeptidase inhibitor from marine mollusk Nerita versicolor in complex with human carboxypeptidase A4. ". J Biol Chem. 2012. PMID 22294694.
  • "Carboxypeptidase 4 gene variants and early-onset intermediate-to-high risk prostate cancer.". BMC Cancer. 2009. PMID 19245716.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ CPA4 - Cronfa NCBI

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