CD1D

CD1D
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	4WO4, 1ZT4, 2PO6, 3HUJ, 3SDX, 3TZV, 3U0P, 3VWJ, 3VWK, 4EN3, 4LHU, 4MNG, 4MQ7, 4WW2
Dynodwyr
Cyfenwau	CD1D, CD1A, R3, R3G1, CD1d molecule
Dynodwyr allanol	OMIM: 188410 HomoloGene: 1337 GeneCards: CD1D
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• beta-2-microglobulin binding; • lipopeptide binding; • GO:0031493 histone binding; • endogenous lipid antigen binding; • lipid antigen binding; • exogenous lipid antigen binding; • cell adhesion molecule binding; • GO:0001948, GO:0016582 protein binding;
Cydrannau o'r gell	• cytoplasm; • integral component of membrane; • endosome; • endoplasmic reticulum membrane; • bilen; • integral component of plasma membrane; • cell surface; • lysosomal membrane; • basolateral plasma membrane; • lysosome; • endosome membrane; • cellbilen; • Reticwlwm endoplasmig; • extracellular space; • external side of plasma membrane;
Prosesau biolegol	• proses y system imiwnedd; • T cell selection; • heterotypic cell-cell adhesion; • positive regulation of T cell proliferation; • detection of bacterium; • positive regulation of innate immune response; • antigen processing and presentation, exogenous lipid antigen via MHC class Ib; • innate immune response; • GO:0022415 viral process; • antigen processing and presentation, endogenous lipid antigen via MHC class Ib; • regulation of immune response; • positive regulation of T cell mediated cytotoxicity; • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response;
	Sources:Amigo / QuickGO
Orthologau
	912
	n/a
	ENSG00000158473
	n/a
	P15813
	n/a
	NM_001766; NM_001319145; NM_001371761; NM_001371762; NM_001371763
	n/a
	NP_001306074; NP_001757; NP_001358690; NP_001358691; NP_001358692
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CD1D yw CD1D a elwir hefyd yn CD1d molecule (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q23.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CD1D.

R3
CD1A
R3G1

Llyfryddiaeth

"CD1d is a novel cell-surface marker for human monocytic myeloid-derived suppressor cells with T cell suppression activity in peripheral blood after allogeneic hematopoietic stem cell transplantation. ". Biochem Biophys Res Commun. 2018. PMID 29108995.
"Blocking of CD1d Decreases Trypanosoma cruzi-Induced Activation of CD4-CD8- T Cells and Modulates the Inflammatory Response in Patients With Chagas Heart Disease. ". J Infect Dis. 2016. PMID 27368347.
"The tumor antigen N-glycolyl-GM3 is a human CD1d ligand capable of mediating B cell and natural killer T cell interaction. ". Cancer Immunol Immunother. 2016. PMID 26969612.
"The actin cytoskeleton modulates the activation of iNKT cells by segregating CD1d nanoclusters on antigen-presenting cells. ". Proc Natl Acad Sci U S A. 2016. PMID 26798067.
"Increased Expression of Two Alternative Spliced Variants of CD1d Molecule in Human Gastric Cancer.". Iran J Immunol. 2015. PMID 26119195.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] CD1D - Cronfa NCBI

[1]

[2]

CD1D

Cyfystyron

Llyfryddiaeth

Cyfeiriadau

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