CBR3

2HRB

CBR3
CBR3
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauCBR3, HEL-S-25, SDR21C2, hcarbonyl reductase 3
Dynodwyr allanolOMIM: 603608 HomoloGene: 20332 GeneCards: CBR3
EC number1.6.5.10 1.1.1.184, 1.6.5.10
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

874

n/a

Ensembl

ENSG00000159231

n/a

UniProt

O75828

n/a

RefSeq (mRNA)

NM_001236

n/a

RefSeq (protein)

NP_001227

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CBR3 yw CBR3 a elwir hefyd yn Carbonyl reductase 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 21, band 21q22.12.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CBR3.

  • hCBR3
  • SDR21C2
  • HEL-S-25

Llyfryddiaeth

  • "Risk factors for anthracycline-associated cardiotoxicity. ". Support Care Cancer. 2016. PMID 26563179.
  • "Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis. ". J Mol Med (Berl). 2012. PMID 22527884.
  • "Expression of human carbonyl reductase 3 (CBR3; SDR21C2) is inducible by pro-inflammatory stimuli. ". Biochem Biophys Res Commun. 2012. PMID 22425771.
  • "Identification of the promoter of human carbonyl reductase 3 (CBR3) and impact of common promoter polymorphisms on hepatic CBR3 mRNA expression. ". Pharm Res. 2009. PMID 19590938.
  • "Functional significance of a natural allelic variant of human carbonyl reductase 3 (CBR3).". Drug Metab Dispos. 2005. PMID 15537833.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ CBR3 - Cronfa NCBI

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