CA12

1JCZ, 1JD0, 4HT2, 4KP5, 4KP8, 4Q0L, 4QJ0, 4QJO, 4QJW, 4WW8

CA12
CA12
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauCA12, CAXII, HsT18816, CA-XII, T18816, carbonic anhydrase 12
Dynodwyr allanolOMIM: 603263 HomoloGene: 20327 GeneCards: CA12
EC number4.2.1.1
Patrwm RNA pattern




Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

771

n/a

Ensembl

ENSG00000074410

n/a

UniProt

O43570

n/a

RefSeq (mRNA)

NM_206925
NM_001218
NM_001293642

n/a

RefSeq (protein)

NP_001209
NP_001280571
NP_996808

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CA12 yw CA12 a elwir hefyd yn Carbonic anhydrase 12 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 15, band 15q22.2.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CA12.

  • CAXII
  • CA-XII
  • T18816
  • HsT18816

Llyfryddiaeth

  • "Essential role of carbonic anhydrase XII in secretory gland fluid and HCO3 (-) secretion revealed by disease causing human mutation. ". J Physiol. 2015. PMID 26486891.
  • "Carbonic anhydrase XII is a new therapeutic target to overcome chemoresistance in cancer cells. ". Oncotarget. 2015. PMID 25686827.
  • "CAXII Is a sero-diagnostic marker for lung cancer. ". PLoS One. 2012. PMID 22439015.
  • "Tumor-associated carbonic anhydrase XII is linked to the growth of primary oral squamous cell carcinoma and its poor prognosis. ". Oral Oncol. 2012. PMID 22172588.
  • "Metabolic acidosis with topiramate and zonisamide: an assessment of its severity and predictors.". Pharmacogenet Genomics. 2011. PMID 21278619.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ CA12 - Cronfa NCBI

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