APOBEC2

2NYT

APOBEC2
APOBEC2
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauAPOBEC2, ARCD1, ARP1, apolipoprotein B mRNA editing enzyme catalytic subunit 2
Dynodwyr allanolOMIM: 604797 HomoloGene: 4941 GeneCards: APOBEC2
EC number3.5.4.36
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

10930

n/a

Ensembl

ENSG00000124701

n/a

UniProt

Q9Y235

n/a

RefSeq (mRNA)

NM_006789

n/a

RefSeq (protein)

NP_006780

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn APOBEC2 yw APOBEC2 a elwir hefyd yn Apolipoprotein B mRNA editing enzyme catalytic subunit 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6p21.1.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn APOBEC2.

  • ARP1
  • ARCD1

Llyfryddiaeth

  • "ARCD-1, an apobec-1-related cytidine deaminase, exerts a dominant negative effect on C to U RNA editing. ". Am J Physiol Cell Physiol. 2001. PMID 11698249.
  • "Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene. ". Proc Natl Acad Sci U S A. 1994. PMID 8078915.
  • "Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis. ". Int J Cancer. 2012. PMID 21469143.
  • "Microarray analysis of tonsils in immunoglobulin A nephropathy patients. ". Biochem Biophys Res Commun. 2010. PMID 20138841.
  • "The APOBEC-2 crystal structure and functional implications for the deaminase AID.". Nature. 2007. PMID 17187054.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ APOBEC2 - Cronfa NCBI

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