AHSA1

AHSA1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1X53
Dynodwyr
Cyfenwau	AHSA1, AHA1, C14orf3, p38, hAha1, activator of Hsp90 ATPase activity 1
Dynodwyr allanol	OMIM: 608466 HomoloGene: 8106 GeneCards: AHSA1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • ATPase activator activity • chaperone binding • GO:0001948, GO:0016582 protein binding • cadherin binding • Hsp90 protein binding Cydrannau o'r gell • extracellular exosome • Reticwlwm endoplasmig • cytoplasm • cytosol Prosesau biolegol • response to stress • positive regulation of ATP-dependent activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10598	n/a
Ensembl	ENSG00000100591	n/a
UniProt	O95433	n/a
RefSeq (mRNA)	NM_012111 NM_001321441	n/a
RefSeq (protein)	NP_001308370 NP_036243	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn AHSA1 yw AHSA1 a elwir hefyd yn Activator of 90 kDa heat shock protein ATPase homolog 1 ac Activator of HSP90 ATPase activity 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 14, band 14q24.3.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn AHSA1.

• "Modulation of the cochaperone AHA1 regulates heat-shock protein 90 and endothelial NO synthase activation by vascular endothelial growth factor. ". Arterioscler Thromb Vasc Biol. 2012. PMID 22859491.
• "Biological and structural basis for Aha1 regulation of Hsp90 ATPase activity in maintaining proteostasis in the human disease cystic fibrosis. ". Mol Biol Cell. 2010. PMID 20089831.
• "AHSA1 regulates proliferation, apoptosis, migration, and invasion of osteosarcoma. ". Biomed Pharmacother. 2016. PMID 26796264.
• "Aha1 can act as an autonomous chaperone to prevent aggregation of stressed proteins. ". J Biol Chem. 2014. PMID 25378400.
• "p38: A novel protein that associates with the vesicular stomatitis virus glycoprotein.". Biochem Biophys Res Commun. 2001. PMID 11554768.