SR 403 begins at an intersection with SR 165 (Kempsville Road/Princess Anne Road), just northeast of the Newtown Road station (the eastern terminus of Hampton Roads Transit's Tide Light Rail). The roadway continues southerly as South Newtown Road (an unnumbered street). From its southern terminus SR 403 heads north-northeasterly through commercial area as Newton Road, a four-lane divided highway that closely parallels the boundary between the cities of Norfolk and Virginia Beach.
Just short of a third of a mile (1⁄2 km) along its route, SR 403 has a partial cloverleaf interchange with I‑264 (Virginia Beach Expressway), with provides access to I-64 (Hampton Roads Beltway)--at the interchange of the Interstate Highways just to the west of the SR 403 interchange. After connecting with multiple minor side streets (Eathan Allen Lane/Cleveland Street, Coliss Avenue, Hawk Street, Elam Avenue, Taft Street, and Seal Street), SR 403 reaches its northern terminus at an intersection with US 58 (Virginia Beach Boulevard). Beyond the intersection Newtown Road continues as an unnumbered highway that enters the city of Virginia Beach.[1][2]