Hughes attended high school in Salida, Colorado, and was nicknamed "Salida Tom".[1] He led the National League in games (50), saves (9), and games finished (22) in 1915; he led the National League in won-loss percentage (.842) in 1916.
Hughes' accomplishments include being the Braves franchise career leader in WHIP (1.022) and hits allowed per nine innings (6.77). He helped the Braves win the 1914 World Series. In nine seasons, Hughes had a 56–39 win–loss record, while appearing in 160 games and pitching 863 innings; he had a 2.56 ERA and 476 strikeouts.