St. Roch Church began as a mission of Our Lady of Mount Carmel Church.[2] The parish was founded in September 1922; Fr Catello Terrone was the first pastor. The altar stone held relics of St. Roch, St. Anthony, St. Lucy, St. Rita and St. Ann. Around 1928 the congregation had grown sufficiently that parishioners went door to door to selling "bricks" for $1 to finance a larger building to replace the small wooden church.[3] The new church building was dedicated in 1929.
Before the opening of the parish school, students were taught in the parish hall. The school was dedicated by Francis Cardinal Spellman in May 1960. The school was staffed by the Sisters of St. John the Baptist.
After almost a decade a declining enrollment, it was among twenty-seven designated by the Archdiocese of New York to close in June 2011.[5][6]