Species of bacterium
Salinispora tropica is an obligate marine actinomycete bacterium species.[ 1] It produces salinosporamide A and salinosporamide B , potential anti-cancer agents,[ 2] [ 3] as well as the polycyclic macrolides sporolide A and B .[ 4]
See also
References
^ a b Maldonado, L. A. (2005). "Salinispora arenicola gen. nov., sp. nov. and Salinispora tropica sp. nov., obligate marine actinomycetes belonging to the family Micromonosporaceae " . International Journal of Systematic and Evolutionary Microbiology . 55 (5): 1759– 1766. doi :10.1099/ijs.0.63625-0 . ISSN 1466-5026 . PMID 16166663 .
^ Fenical, W.; Jensen, P.R.; Palladino, M.A.; Lam, K.S.; Lloyd, G.K.; Potts, B.C. (2009). "Discovery and development of the anticancer agent salinosporamide A (NPI-0052)" . Bioorganic & Medicinal Chemistry . 17 (6): 2175– 2180. doi :10.1016/j.bmc.2008.10.075 . PMC 2814440 . PMID 19022674 .
^ Williams PG; Buchanan GO; Feling RH; Kauffman CA; Jensen PR; Fenical W (August 2005). "New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica". The Journal of Organic Chemistry . 70 (16): 6196– 203. doi :10.1021/jo050511+ . PMID 16050677 .
^ Buchanan, Greg O.; Williams, Philip G.; Feling, Robert H.; Kauffman, Christopher A.; Jensen, Paul R.; Fenical, William (2005). "Sporolides a and b: Structurally Unprecedented Halogenated Macrolides from the Marine Actinomycete Salinispora tropica ". Organic Letters . 7 (13): 2731– 2734. doi :10.1021/ol050901i . PMID 15957933 .
Further reading
Udwary DW, Zeigler L, Asolkar RN, et al. (June 2007). "Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica " . Proceedings of the National Academy of Sciences of the United States of America . 104 (25): 10376– 81. Bibcode :2007PNAS..10410376U . doi :10.1073/pnas.0700962104 . PMC 1965521 . PMID 17563368 .
Bucarey, S. A.; Penn, K.; Paul, L.; Fenical, W.; Jensen, P. R. (2012). "Genetic Complementation of the Obligate Marine Actinobacterium Salinispora tropica with the Large Mechanosensitive Channel Gene mscL Rescues Cells from Osmotic Downshock" . Applied and Environmental Microbiology . 78 (12): 4175– 4182. doi :10.1128/AEM.00577-12 . ISSN 0099-2240 . PMC 3370544 . PMID 22492446 .
Thuan, Nguyen Huy; Yamaguchi, Tokutaro; Lee, Joo Ho; Sohng, Jae Kyung (2013). "Characterization of sterol glucosyltransferase from Salinispora tropica CNB-440: Potential enzyme for the biosynthesis of sitosteryl glucoside". Enzyme and Microbial Technology . 52 (4– 5): 234– 240. doi :10.1016/j.enzmictec.2013.02.004 . ISSN 0141-0229 . PMID 23540924 .
External links