Lozano started his career with Quilmes.[3][4] He was picked for his senior debut in May 2017 against Gimnasia y Esgrima in the Copa Argentina, with the defender playing the full duration of a penalty shoot-out defeat.[3] In the succeeding June, Lozano was an unused substitute on two occasions in the Primera División but never made it on as Quilmes suffered relegation in 2016–17.[3] His professional bow eventually arrived in the 2018–19 Primera B Nacional on 27 August 2018 versus Atlético de Rafaela, as Lozano started and finished the opening seventeen matches of Quilmes' season; only missing game eighteen due to suspension.[3][5][6]
In July 2020, Lozano joined Huracán on loan for the rest of the year, with an option to extend the loan with one year, if Lozano had played 50% of the games for Huracán.[7] In January 2021, the deal was extended for one year, until the end of 2021.[8] In January 2022, Lozano was loaned out to fellow league club Patronato until the end of 2022 with a purchase option.[9]
