Pyrobaculum asR3 small RNA

xxx sRNA
Predicted secondary structure and sequence conservation of Pyrobaculum asRNA3
Identifiers
Rfam	RF02793
Other data
Domain(s)	Archaea
GO	GO:0003729
SO	SO:0000077,SO:0000370
PDB structures	PDBe

asR3 is an archeal small RNA identified in seven Pyrobaculum species. The genus-specific nature can indicate this could be recent, stable adaptation.^[1] asR3 binds to the 3′-end of the tpi gene (triose-phosphate-isomerse).^[2] The tpi mRNA has a conserved structural element located close to the stop codon. Binding of the asR3 may be able to compete against the formation of the tpi element structure and this may modulate the function of this highly conserved element.^[1]

References

1. Bernick DL, Dennis PP, Lui LM, Lowe TM (2012). "Diversity of Antisense and Other Non-Coding RNAs in Archaea Revealed by Comparative Small RNA Sequencing in Four Pyrobaculum Species". Frontiers in Microbiology. 3: 231. doi:10.3389/fmicb.2012.00231. PMC 3388794. PMID 22783241.
2. Alber T, Banner DW, Bloomer AC, Petsko GA, Phillips D, Rivers PS, Wilson IA (June 1981). "On the three-dimensional structure and catalytic mechanism of triose phosphate isomerase". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 293 (1063): 159–171. doi:10.1098/rstb.1981.0069. PMID 6115415.

See also

Other archaeal sRNAs:

• Archaeal H/ACA sRNA
• Methanosarcina sRNA162