Born in Tbilisi, Surguladze studied singing with Guliko Kariauli at the Tbilisi State Conservatoire.[2] After winning a prize at the Francisco Viñas International Singing Contest in Barcelona, she earned her a scholarship at the Accademia of the Teatro alla Scala [it],[3][2][4] where she studied with Leyla Gencer and Luciana Serra.[5] She made her operatic debut as Cuniza in Verdi's Oberto and Zulma in Rossini's L'italiana in Algeri in Milan in 2002,[6][7] and has since appeared in many opera houses around the world.
She has appeared in the Italian television film Rigoletto a Mantova (2010) and in the Georgian films Valsi Pechoraze[8] and Metichara.[9] In 2010, she was awarded the Presidential Order of Excellence by Mikhail Saakashvili.[10][11] In 2018 she appeared in the title role of a video-recorded performance of Bizet's Carmen by the Opéra Royal de Liège.
Surguladze is a founder of the charity foundation Desire Tree, which aims to provide assistance to children in need of medical care.[12][13]