Kaklamanis was born in Andros. Kaklamanis studied medicine at the Medical School of the University of Athens. His medical training was spent in Ioannina. From 1975 to 1981, he worked at the Aretaieio Hospital in Athens, first as an assistant and then as a registrar. He qualified as a radiation oncologist, his second specialisation, in 1980. He was awarded his doctorate in 1981. He served as secretary-general to the Panhellenic Medical Association from 1984 to 1989 and was elected on the ND ticket. In 1989, he was elected Assistant Professor of Radiotherapy–Oncology at the University of Athens.
In popular culture
Some of his rivals or haters nicknamed him "Omer Prioni" (a pun of the Albanian Name Vrioni and the Greek word prioni. Prioni means "saw" in Greek language) or Nikitaras the Woodeater (a pun of the Greek 1821 Revolution Hero Nikitaras the Turkeater) because Nikita Kaklamanis cut a lot of trees.
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