Netarsudil/latanoprost

Netarsudil/latanoprost

Combination of
Netarsudil	Rho kinase inhibitor
Latanoprost	Prostaglandin F2α analogue
Clinical data
Trade names	Rocklatan, Roclanda
AHFS/Drugs.com	Professional Drug Facts
License data	US DailyMed: Netarsudil and latanoprost
Routes of administration	Eye drops
ATC code	S01EE51 (WHO)
Legal status
Legal status	US: ℞-only[1] EU: Rx-only[2][3]
Identifiers
KEGG	D11558

Netarsudil/latanoprost, sold under the brand name Rocklatan among others, is a fixed-dose combination medication use to treat elevated intraocular pressure (IOP) in people with open-angle glaucoma or ocular hypertension.^[1][2] It contains netarsudil mesylate and latanoprost.^[1][2] It is applied as eye drops to the eyes.^[1][2]

The most common side effects include conjunctival hyperaemia (red eye), pain at the site where the medicine was applied, cornea verticillata (deposits in the cornea, the transparent layer in front of the eye that covers the pupil and iris), pruritus (itching of the eye), erythema (reddening) and discomfort in the eye, increased lacrimation (watery eyes), and conjunctival haemorrhage (bleeding in the surface layer of the eye).^[2]

Netarsudil/latanoprost was approved for medical use in the United States in March 2019,^[4] and in the European Union in January 2021.^[2]

Medical uses

Netarsudil/latanoprost is indicated for the reduction of elevated intraocular pressure (IOP) in adults with primary open-angle glaucoma or ocular hypertension.^[1][2]

References

1. "Rocklatan- netarsudil and latanoprost ophthalmic solution, 0.02%/0.005% solution/ drops". DailyMed. 10 March 2020. Retrieved 2 June 2020.
2. "Roclanda EPAR". European Medicines Agency (EMA). 9 November 2020. Retrieved 22 January 2021. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
3. "Roclanda Product information". Union Register of medicinal products. Retrieved 3 March 2023.
4. "Drug Approval Package: Rocklatan Ophthalmic Solution". U.S. Food and Drug Administration (FDA). 20 November 2019. Retrieved 2 June 2020.