NGC 4299 has a truncated Hα disk with the outer extent of the Hα having an irregular distribution except in the southwest where it forms a well-defined ridge. This appears to be the result of ram-pressure.[12]
Interaction with NGC 4294
As a result of a tidal interaction with NGC 4294, NGC 4299 has a disturbed optical and HI morphology,[16][11] with asymmetric spiral arms, a small, weak bar[10] and a high global star formation rate that appears to have been enhanced by ram-pressure.[12]
HI tail
Chung et al. identified that NGC 4299 has a one sided[17][18] tail of neutral atomic hydrogen (HI).[10][19] The tail points to the southwest[17][8] and appears to be a result of ram-pressure[19][20][10] or by a tidal interaction with NGC 4294.[10] The tail has no optical counterpart[10][17] and is oriented parallel to the HI tail found in NGC 4294.[17]
NGC 4299 appears to have a second tail pointing to the southeast that is much broader and lower in HI surface density than the main tail.[17]
^Binggeli, B.; Sandage, A.; Tammann, G. A. (September 1985). "Studies of the Virgo Cluster. II - A catalog of 2096 galaxies in the Virgo Cluster area. V - Luminosity functions of Virgo Cluster galaxies". The Astronomical Journal. 90: 1681. Bibcode:1985AJ.....90.1681B. doi:10.1086/113874. ISSN0004-6256.
^Boker, Torsten; Sarzi, Marc; McLaughlin, Dean E.; van der Marel, Roeland P.; Rix, Hans-Walter; Ho, Luis C.; Shields, Joseph C. (2004-01-01). "A Hubble Space Telescope Census of Nuclear Star Clusters in Late-Type Spiral Galaxies. II. Cluster Sizes and Structural Parameter Correlations". The Astronomical Journal. 127 (1): 105–118. arXiv:astro-ph/0309761. Bibcode:2004AJ....127..105B. doi:10.1086/380231. ISSN0004-6256. S2CID16746074.
^Warmels, R. H. (1988-01-01). "The H I properties of spiral galaxies in the Virgo Cluster. I - Westerbork observations of 15 Virgo Cluster galaxies. II - One-dimensional Westerbork observations of 21 galaxies". Astronomy and Astrophysics Supplement Series. 72: 19–87. Bibcode:1988A&AS...72...19W. ISSN0365-0138.