The station was established by Johan A. Olsen in 1922, who named the place appropriately, for it is located in one of the worst mosquito-infested areas of Eastern Greenland (Norwegian: mygg). However, on the way back to Norway in 1923, the Norwegian sealer ANNI 1 which had brought the expedition to Greenland in 1922 was crushed in the offshore pack ice and all men on board perished. Thus the station was discontinued after only one year of operation.[3]
In 1924 Myggbukta station was repaired by Gunnar Isachsen and it was manned by the Foldvik expedition in 1926. In 1930 was completely rebuilt and operation was continuous, sending daily weather reports from the site. On 27 June 1931 five Norwegian hunters with Hallvard Devold annexed Erik the Red's Land to Norway from the station, proclaiming:
"In the presence of Eiliv Herdal, Tor Halle, Ingvald Strøm and Søren Richter, the Norwegian flag is now hoisted in Mosquito Bay. And the land between Carlsberg Fjord in the south and Bessel Fjord in the north is occupied in His Majesty King Haakon's name."[4]
Myggbukta thus served as de facto capital of this short-lived Norwegian territory, although sysselman ("Governor") Helge Ingstad overwintered at the more southerly station Antarctic Havn.[3]