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A mutant is a biological entity which has undergone a change in its genetic structure.

Mutant or mutants may also refer to:

Books and comics

Mutant (Marvel Comics), a human being who is born with genetic modifications that allow for abilities not possessed by regular humans
Mutant (short story collection), a collection of science fiction short stories by Lewis Padgett
Mutants (short story collection), a collection of short stories by Gordon R. Dickson
Mutants in fiction, a common trope in science fiction and comic books
Mutants: On Genetic Variety and the Human Body, a book by Armand Marie Leroi
The Mutants, by Kris Neville 1966
The Mutants, by Berni Wrightson 1980

"The Mutant", a 1964 episode of The Outer Limits
The Mutants, another title used for the 1963 Doctor Who serial The Daleks, not to be confused with the 1972 serial below
The Mutants, a 1972 Doctor Who serial
"Mutants", a 2004 episode of The Mighty Boosh

Mutant (role-playing game), a series of Swedish role-playing games developed and published by Target Games
- Mutant (role-playing game 1984) or "Old Mutant", the original release
Mutants: Genetic Gladiators, a 2014 Kobojo game

The Mutants (San Francisco band), a punk rock band
The Mutants (UK band), a punk rock musical collaboration with an all-star cast of guest musicians
Mutant (album), a 2015 album by Arca
Mutant Vol. 2, a follow-up album to the Man's Myth Vol. 1 album (collectively known as Man's Myth & Mutant) by horror-core band Twiztid
Mutants (John Dahlbäck album), 2010
Mutants (Mutoid Man album), 2023