Midol was originally sold in 1911 as a headache and toothache remedy that was considered safer because it did not use the narcotics typically used at the time.[1] It was then promoted as a cure for hiccups claiming it controlled spasms, and finally as a remedy for menstrual cramps and bloating.[2][3][4][5] A formulation sold in the 1980s was made with the sympathomimeticcinnamedrine.[6] It had been reported to have abuse potential as an appetite suppressant and sympathomimetic agent. Midol, like other NSAID class of drugs, may have side effects for some, such as an increased risk of bleeding, kidney damage or negative effects on cardiovascular system.[7]
