In December 2021, Jenkins was recommended to the president by Senators Dick Durbin and Tammy Duckworth.[12] On July 14, 2022, President Joe Biden announced his intent to nominate Jenkins[13] to serve as a United States district judge of the United States District Court for the Northern District of Illinois.[3] On September 19, 2022, her nomination was sent to the Senate. President Biden nominated Jenkins to the seat vacated by Judge John Z. Lee, who was elevated to the United States Court of Appeals for the Seventh Circuit on September 12, 2022.[14] On October 12, 2022, a hearing on her nomination was held before the Senate Judiciary Committee.[15] On December 1, 2022, her nomination was reported out of committee by a 15–7 vote.[16] On January 3, 2023, her nomination was returned to the President under Rule XXXI, Paragraph 6 of the United States Senate; she was renominated later the same day.[17] On February 2, 2023, her nomination was reported out of committee by a 14–6 vote.[18] On February 14, 2023, the Senate invoked cloture on her nomination by a 58–41 vote.[19] That same day, her nomination was confirmed by a 59–40 vote.[20] She received her judicial commission on February 24, 2023.[21]
She was sworn in on February 27, 2023.[22]
Notable rulings
On April 18, 2023, Jenkins dismissed a lawsuit against a school district by a parent claiming his parental rights were violated under the 14th Amendment, alleging the school district facilitated his child's gender transition.[23]
On April 27, 2023, Jenkins declined to block enforcement of the Protect Illinois Communities Act, an assault weapons ban. In reasoning that the assault weapons ban is consistent with the Supreme Court holding in Bruen, Jenkins said "because assault weapons are particularly dangerous weapons and high-capacity magazines are particularly dangerous weapon accessories, their regulation accords with history and tradition."[24] The 7th Circuit subsequently affirmed Jenkins' ruling on November 4, 2023.[25]