Evans garnered attention in early 2018 when she directed the music video for Drake's single "God's Plan"; the video went viral and the song reached number one on the Billboard Hot 100. The video depicts Drake donating his $1 million production budget to the people of Miami.[13] Evans subsequently directed his "Nice for What" music video, which garnered critical acclaim from several publications.[14][15] Evans referred to the video as a "celebration of women",[11] as the video featured iconic female stars such as Olivia Wilde and Issa Rae. Vogue lauded Evans as "surely destined to be the starriest young video director in the firmament".[16] Later that year, she became the first woman to win the Prism Prize's Lipsett Award for music video direction.[1][17] That year, Director X posted a congratulations to Evans with this caption:
"@karenaevans started as an intern. She stayed longer worked harder than everyone else. From intern to director at my company. Last year grinding on low budget jobs giving big budget results. This year she’s directed @champagnepapi God’s Plan & the new single Nice For What. When work ethic is matched by talent. Big up the team @popp_rok for pulling this wide ranging job off. Here’s some bts footage for all y’all 🙌🏽 (feel like a Dad video taping his daughter at a recital when ever I come to set)"[11]
In late 2018, Evans earned Much Music Video Award and MTV Video Music Award nominations for her work on Drake's videos.[22] She ultimately won Best Director at the 2018 iHeartRadio MMVAs for her work on "God's Plan".[23] In 2020, Evans was placed on BET's "Future 40" list, which is a list of “40 of the most inspiring and innovative vanguards who are redefining what it means to be unapologetically young, gifted, and black”.[24]
Evans is the younger sister of Jordan Evans, a producer who has worked with several successful artists, and was inspired by him to pursue her passion.[27] Evans has stated that she is heavily influenced by Melina Matsoukas, whom she called her "hero" in an interview with Billboard.[22] Evans hopes to be an inspiration for other young black women from her hometown of Toronto.[27]