During his tenure as a federal judge, Miller has handled some noteworthy cases.[3] In 2005 he presided over a corruption case against San Diego City CouncilmembersRalph Inzunza and Michael Zucchet. After the jury convicted both men and a co-defendant, Miller took the unusual step of overturning the jury verdict against Zucchet and acquitting him on most of the charges, saying the evidence against him was insufficient. The ruling was upheld by the Ninth Circuit Court of Appeals.
In 2013 he presided over a case against four Somali immigrants who were accused of sending money to the terrorist group al-Shabab. The case used information gathered by a secret National Security Agency (NSA) program for collecting telephone metadata. He sentenced the men to prison; his rulings regarding the NSA's surveillance program were affirmed on appeal.[3]
In November 2016, Miller successfully brokered settlement talks in three separate lawsuits against Donald Trump alleging fraudulent practices by Trump University.[3][4]