Watson was born in Woodbury, Connecticut on April 6, 1750. He graduated from Yale College in 1776, and was commissioned a lieutenant in the Connecticut regiment. He retired as a captain in 1777 and studied law. Watson moved to New York City in 1786 and became a merchant at 44 Broad Street. He was a member of the New York State Assembly in 1791, 1794–1796 and was Speaker in 1794. He was a member of the New York State Senate (Southern District) from 1796 to 1798 and was a Regent of New York University from 1795 until his death.[1]
In 1798, Watson was elected as a Federalist to the United States Senate to fill the vacancy caused by the resignation of John Sloss Hobart and served in the 5th and 6th United States Congress from December 11, 1798, to March 19, 1800, when he resigned to accept an appointment by President John Adams as Naval Officer of the Port of New York.[1]
Watson’s townhouse, located at 7 State Street in New York City still stands and is on the National Register of Historic Places.[2] It was also the residence of Elizabeth Ann Seton, the first American Catholic Saint. The home is currently occupied by the rectory of the Our Lady of the Holy Rosary Church and is part of the Seton Shrine.[3]