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From 1964 to 1969, he held the position of chief of the service of pre-operative diagnosis at the Clinic of Neurosurgery of the University of Bucharest under Constantin Arseni [ro]. With Arseni and Frank Nass, Petrovici authored Vascular Diseases of the Brain and of the Spinal Cord in 1965.
In 1969, he emigrated to Germany and began his activity in Cologne at the Max Planck Institute for Brain Research under Klaus-Joachim Zülch [de]. Despite his time-consuming clinical responsibilities during this period, he began to apply his research training to neurologic problems. He was habilitated into academic career (venia legendi) in 1978 and in 1983 became professor of neurology and psychiatry at the University of Cologne. In 1985 he was appointed director of the Department of Neurology at Merheim Hospital at the university. He held this position until his retirement in 1994.