Gmina Perzów is a rural gmina (administrative district) in Kępno County, Greater Poland Voivodeship, in west-central Poland. Its seat is the village of Perzów, which lies approximately 12 kilometres (7 mi) west of Kępno and 139 km (86 mi) south-east of the regional capital Poznań.
The gmina covers an area of 75.46 square kilometres (29.1 sq mi), and as of 2006 its total population is 3,925.