GET4

GET4
Identifiers
Aliases	GET4, C7orf20, CEE, TRC35, CGI-20, golgi to ER traffic protein 4, guided entry of tail-anchored proteins factor 4
External IDs	OMIM: 612056; MGI: 1914854; HomoloGene: 41080; GeneCards: GET4; OMA:GET4 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7p22.3 Start 876,554 bp[1] End 896,436 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 G2 Start 139,238,079 bp[2] End 139,255,806 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left testis right testis Pituitary Gland right adrenal cortex left adrenal cortex right uterine tube anterior pituitary right lobe of liver skin of leg skin of abdomen Top expressed in bone marrow yolk sac epiblast layer of retina neural layer of retina proximal tubule neural tube adrenal gland limb lip More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding chaperone binding Cellular component BAT3 complex cytosol cytoplasm nucleoplasm nucleolus Biological process cytoplasmic sequestering of protein tail-anchored membrane protein insertion into ER membrane maintenance of unfolded protein involved in ERAD pathway protein insertion into ER membrane Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51608 67604 Ensembl ENSG00000239857 ENSMUSG00000025858 UniProt Q7L5D6 Q9D1H7 RefSeq (mRNA) NM_015949 NM_001163316 NM_026269 NM_001359238 RefSeq (protein) NP_057033 NP_001156788 NP_080545 NP_001346167 Location (UCSC) Chr 7: 0.88 – 0.9 Mb Chr 5: 139.24 – 139.26 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

GET4 is a protein that in humans is encoded by the GET4 gene.^[5][6]

References

1. GRCh38: Ensembl release 89: ENSG00000239857 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000025858 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
6. "Entrez Gene: C7orf20 chromosome 7 open reading frame 20".

External links

• Human GET4 genome location and GET4 gene details page in the UCSC Genome Browser.

Further reading

• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
• Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.